Recombinant Monkey CD160 Protein, His-tagged, Alexa Fluor 488 conjugated

CD160 antigen, also known as Natural killer cell receptor BY55 and CD160, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymph centigradeyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and small intestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymph centigradeytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD160+ lymph centigradeyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymph centigradeytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymph centigradeyte responsiveness.

• Supplier: Creative Biomart
• Product #: CD160-314RAF488
• Product Category: Recombinant Protein
• Shipping Country: USA