L-732138
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-101249-10 mM * 1 mL |
| CAS # | 148451-96-1 |
| Pricing | 10 mM * 1 mL, USD $239.0 |
| Biological Activity | L-732138 is a selective, potent and competitive neurokinin-1 (NK-1) receptor antagonist with an IC50 of 2.3 nM. L-732138 has 200-fold more potent in cloned human NK-1 receptors than cloned rat NK-1 receptors, and has > 1000-fold more potent than human NK-2 and NK-3 receptors. L-732138 can reduce hyperalgesia and has antitumor action[1][2]. |
| Purity | ≥99.0% |
| MWt | 472.38 |
| Formula | C₂₂H₁₈F₆N₂O₃ |