PMX 205 acetate

PMX 205 acetate is a potent complement C5a receptor antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease.

• Supplier: BOC Sciences
• Product #: BAT-016404
• Molecular Weight: 899.09
• Molecular Formula: C47H66N10O8
• Canonical SMILES: CC(=O)O.C1CCC(CC1)CC2C(=O)NC(C(=O)NC(C(=O)NCCCC(C(=O)N3CCCC3C(=O)N2)NC(=O)CCC4=CC=CC=C4)CCCN=C(N)N)CC5=CNC6=CC=CC=C65