Anti-March5 Antibody
Membrane-associated RING-CH protein 5 (March5), also known as NKP66, is thought to be a mitochondrial ubiquitin ligase that is localized on the mitochondrial membrane. March5 has a Plant Homeo-Domain (PHD) motif that is essential for E3 ubiquitin ligase action. MARCH 5 is also thought to have four transmembrane domains. March5 has been associated with mitochondrial fission and division. March5 also seems to have a defensive role against mitochondrial dysfunction by interacting with mutant superoxide dismutase 1 (mSOD1) and preventing mSOD1 from causing damage. mSOD1 damage has been linked to the onset and progression of amyotrophic lateral sclerosis.
| Supplier | Creative Biogene |
|---|---|
| Product # | PAB1039 |
| Pricing | Inquiry |
| Research Area | Primary Antibodies/Antibody |
| Antibody Target | Antibody Target : |
| Antibody Type | Polyclonal |
| Application | WB, ICC |
| Formulation | Rabbit polyclonal serum containing 0.05% sodium azide. |
| Appearance | Liquid |
| Host | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Usage Statement | Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses. |