Regulator of Nonsense Transcripts 1 (UPF1) Antibody
UPF1 Antibody is a Rabbit Polyclonal antibody against UPF1. Upf1 was identified as an active component in nonsense-mediated decay (NMD), an mRNA surveillance mechanism in eukaryotic cells that degrades mRNAs containing premature termination codonsUpf1 was found to be an ATP-dependent RNA helicase in the cytoplasm and was later shown to be a component of cytoplasmic P-bodiesUpf1 phosphorylation mediates the repression of translation that accompanies NMD, allowing mRNA accessibility to the NMD machineryTwo other active components of NMD, Upf2 and Upf3, were also identified and described as having perinuclear and nucleocytoplasmic localization, respectively.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx117103-100UL |
| Pricing | 100 µl USD $522.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | ELISA, WB, IHC |
| UniProt Primary AC | Q92900 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |