SMBA 1
SMBA 1 is a selelctive and high affinity Bax activator (Ki = 43.3 nM) that binds to the S184 binding pocket and inhibits Bax phosphorylation. SMBA 1 exhibits no affinity for other Bcl-2 family members, including Bcl-2, Bak and Bid. SMBA 1 induces apoptosis in lung cancer cell lines which expresses high levels of Bax.
Supplier | BOC Sciences |
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Product # | 906440-37-7 |
Pricing | Inquire |
Cas | 906440-37-7 |
Molecular Weight | 315.32 |
Molecular Formula | C20H13NO3 |
Canonical SMILES | C1=CC=C(C(=C1)C=C2C3=CC=CC=C3C4=C2C=C(C=C4)[N+](=O)[O-])O |