Org-6906
Org-6906 is a dual of monoamine uptake inhibitor and α2 adrenoceptor antagonist potentially for the treatment. Org-6906 facilitated potassium-stimulated release of noradrenaline from slices of cortex, displaced [3H]rauwolscine and [3H]dihydroergocryptine from their binding sites but only weakly blocked alpha 1-adrenoceptors. The alpha 2-adrenolytic properties were also apparent in behavioural interaction models. The compound antagonized the sleep-inducing effects of clonidine in chicks and mice and it antagonized the mydriasis induced by clonidine in the rat.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1062 |
| CAS # | 67384-25-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | Org-6906; Org 6906; Org6906; Org-6906 free |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C13H16ClN |
| Molecular Weight | 221.728 |
| Elemental Analysis | C, 70.42; H, 7.27; Cl, 15.99; N, 6.32 |
| IUPAC/Chemical Name | 5,8,9,10-tetrahydro-5,9-methanobenzo[8]annulen-8-amine hydrochloride |
| InChi Key | FTKXWCQSVJPWPZ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C13H15N.ClH/c14-13-6-5-10-8-11(13)7-9-3-1-2-4-12(9)10;/h1-6,10-11,13H,7-8,14H2;1H |
| SMILES Code | NC1C2CC3=CC=CC=C3C(C2)C=C1.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |