PA-8
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133529 |
| CAS # | 878437-15-1 |
| Pricing | inquire |
| Biological Activity | PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1-, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC50 of 2 nM[1][2]. |
| MWt | 342.35 |
| Formula | C₁₇H₁₈N₄O₄ |