BP897
BP897 is a potent (K(i) = 0.92 nM) dopamine D(3) receptor compound developed for the treatment of cocaine abuse and craving. BP 897 has a high selectivity for the dopamine D(3) versus D(2) receptors (70-fold) and a moderate affinity for 5-HT(1A) receptors, (K(i) = 84 nM), adrenergic-alpha(1) (K(i) = 60 nM) and -alpha(2) adrenoceptors (K(i) = 83 nM). BP 897 displays significant intrinsic activity at the human dopamine D(3) receptor by decreasing forskolin-stimulated cAMP levels and by stimulating mitogenesis of dopamine D(3)-expressing NG108-15 cells.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1427 |
| CAS # | 314776-92-6 |
| Pricing | Customizable size, Inquiry |
| Synonym | BP897; BP-897; BP 897. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C26H31N3O2 |
| Exact Mass | 417.2416 |
| Molecular Weight | 417.553 |
| Elemental Analysis | C, 74.79; H, 7.48; N, 10.06; O, 7.66 |
| IUPAC/Chemical Name | N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide |
| InChi Key | MNHDKMDLOJSCGN-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C26H31N3O2/c1-31-25-11-5-4-10-24(25)29-18-16-28(17-19-29)15-7-6-14-27-26(30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20H,6-7,14-19H2,1H3,(H,27,30) |
| SMILES Code | O=C(NCCCCN1CCN(C2=CC=CC=C2OC)CC1)C3=CC=C4C=CC=CC4=C3 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |