Gefitinib-based PROTAC 3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-123921-5 mg |
| CAS # | 2230821-27-7 |
| Pricing | 5 mg, USD $120.0 |
| Biological Activity | Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively[1]. |
| Purity | 99.98% |
| MWt | 934.51 |
| Formula | C₄₇H₅₇ClFN₇O₈S |