Leptomycin B
Leptomycin B (LMB, CI 940, Elactocin, Mantuamycin, NSC 364372) is a potent antifungal antibiotic isolated from Streptomyces and acts as a specific inhibitor of the nuclear export factor CRM1. Leptomycin B rapidly induces cytotoxic effects in cancer cell lines via covalent inhibition of CRM1 with IC50 values of 0.1 nM–10 nM.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S7580 |
| Sku # | S7580-1mg |
| Pricing | 1mg, $279.00 |