IK1 inhibitor PA-6
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112544-10 mM * 1 mL |
| CAS # | 500715-03-7 |
| Pricing | 10 mM * 1 mL, USD $87.0 |
| Synonyms | PA-6 |
| MWt | 492.61 |
| Formula | C₃₁H₃₂N₄O₂ |
| Biological Activity | IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia[1][2][3]. |
| Purity | 98.23% |