AZD3839 free base
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13438-10 mg |
| CAS # | 1227163-84-9 |
| Pricing | 10 mg, USD $240.0 |
| Biological Activity | AZD3839 free base is a potent and selective orally active, brain-permeable BACE1 inhibitor (Ki=26 nM). AZD3839 free base shows 14 and >1000-fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose- and time-dependent lowering of plasma, brain, and cerebrospinal fluid Aβ levels in mouse, guinea pig, and non-human primate. AZD3839 free base can be used for the research of Alzheimer's disease[1][2]. |
| Purity | 99.99% |
| MWt | 431.41 |
| Formula | C₂₄H₁₆F₃N₅ |