Phospho-RSK3 (Thr356/Ser360) Antibody

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Supplier CD BioSciences
Product # AMA-0036
Pricing 100 μL, Inquire
Product Category Antibodies
Application WB, IP
Product Usage Information Dilution Western Blotting (1:1000); Immunoprecipitation (1:50)
Reactivity Human, Monkey, Mouse, Rat
Gene ID 6197
UniProt ID
MW (Target) 90 kDa
Storage Store at -20°C.
Purification Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr356/Ser360 of human RSK3. Antibodies are purified by protein A and peptide affinity chromatography.
Background The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation. RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters.
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