Fedratinib hydrochloride hydrate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10409A-5 mg |
| CAS # | 1374744-69-0 |
| Pricing | 5 mg, USD $50.0 |
| Synonyms | TG-101348 hydrochloride hydrate; SAR 302503 hydrochloride hydrate |
| MWt | 615.62 |
| Formula | C₂₇H₄₀Cl₂N₆O₄S |
| Biological Activity | Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2]. |
| Purity | 99.82% |