(S)-3-Hydroxy Midostaurin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108263A |
| CAS # | 945260-14-0 |
| Pricing | inquire |
| Biological Activity | (S)-3-Hydroxy Midostaurin ((S)-CGP52421) is a potent kinases inhibitor with IC50 values of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et). (S)-3-Hydroxy Midostaurin is a minor metabolite of midostaurin (PKC412; HY-10230) undergoing by the hepatic CYP3A4 enzyme. (S)-3-Hydroxy Midostaurin has the potential for acute myeloid leukemia (AML)[1]. |
| Synonyms | (S)-CGP52421 |
| MWt | 586.64 |
| Formula | C₃₅H₃₀N₄O₅ |