Tasimelteon
Tasimelteon (trade name Hetlioz) is a drug approved by the FDA solely for the treatment of non-24-hour sleep–wake disorder (often designated as N24HSWD) in totally blind adults. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to other members of the melatonin receptor agonist class of which ramelteon (2005) and agomelatine (2009) were the first approved.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1336 |
| CAS # | 609799-22-6 |
| Pricing | Customizable size, Inquiry |
| Synonym | BMS214778, BMS-214778, BMS 214778, VEC162, VEC-162, VEC 162, Tasimelteon, Hetlioz |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C15H19NO2 |
| Exact Mass | 245.14158 |
| Molecular Weight | 245.32 |
| Elemental Analysis | C, 73.44; H, 7.81; N, 5.71; O, 13.04 |
| IUPAC/Chemical Name | N-(((1R,2R)-2-(2,3-dihydrobenzofuran-4-yl)cyclopropyl)methyl)propionamide |
| InChi Key | PTOIAAWZLUQTIO-GXFFZTMASA-N |
| InChi Code | InChI=1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1 |
| SMILES Code | CCC(NC[C@H]1[C@H](C2=C3CCOC3=CC=C2)C1)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO. |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |