| Supplier |
Creative Peptides |
| Product # |
R1590 |
| CAS # |
127317-03-7 |
| Pricing |
Inquire
|
| Synonyms |
PACAP 1-27, Pituitary Adenylate Cyclase Activating Polypeptide,
|
| MolecularFormula |
C142H224N40O39S
|
| MolecularWeight |
3147.66
|
| Source |
Synthetic
|
| Sequence |
- One Letter Code: HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH2
- Three Letter Code: His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2
|
| Storage |
−20°C
|
| ShippingCondition |
Shipped at room temperature
|
| Explanation |
PACAP (1-27), human, ovine, rat, the N-terminal fragment of PACAP-38, is a potent PACAP receptor antagonist with IC50s of 3, 2, and 5 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2.
|
| InChIKey |
RZGBUJXSKLDAFE-QYHUGZLJSA-N
|
| CanonicalSMILES |
CC[C@H](C)[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@H](Cc2ccc(cc2)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc3ccc(cc3)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CCC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc4ccc(cc4)O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N)NC(=O)CNC(=O)[C@@H](CC(=O)O)NC(=O)[C@@H](
|
| Solubility |
Soluble to 1 mg/ml in water
|
| Appearance |
White to off-white solid
|
| Purity |
≥98% by HPLC
|