| Supplier |
Creative Peptides |
| Product # |
AF3352 |
| Pricing |
Inquire
|
| MolecularWeight |
1640.1
|
| Sequence |
- One Letter Code: FVQWFSKFLGRIL-NH2
- Three Letter Code: H-Phe-Val-Gln-Trp-Phe-Ser-Lys-Phe-Leu-Gly-Arg-Ile-Leu-NH2
|
| Storage |
-20°C
|
| Explanation |
Temporin L is a hydrophobic peptide amide derived from the frog Rana temporaria. This peptide penetrates the hydrophobic core of the cell membrane to penetrate and disrupt the lipid bilayer. Temporin L enhances Temporin A and Temporin B activity by preventing their oligomerization to Lipopolysaccharide (LPS), allowing them to bypass LPS and access the cytoplasmic membrane. This peptide is active against Gram-positive and Gram-negative bacteria, including B. megaterium and E. coli.
|
| Reference |
- 1. Rosenfeld, Y. et al. J Biol Chem 281, 28565 (2006);
- 2. Simmaco, M. et al. Eur J Biochem 242, 788 (1996);
- 3. Zhao, H. et al. J Biol Chem 277, 25170 (2002).
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