SN-6

SN-6 is a selective Na+/Ca2+-exchange (NCX) inhibitor that displays some selectivity for NCX1 (IC50 = 2.9, 16 and 8.6 μM for inhibition of intracellular Na+-dependent 45Ca2+ uptake by cells expressing NCX1, NCX2 and NCX3, respectively). SN-6 shows some affinity for mACh receptors (IC50 = 18 μM) but minimal activity against NCKX2 and various receptors and ion channels (IC50 > 30 μM). SN-6 exhibits anti-ischemic activity.

• Supplier: BOC Sciences
• Product #: 415697-08-4
• Cas: 415697-08-4
• Molecular Weight: 402.16
• Molecular Formula: C20H22N2O5S
• Canonical SMILES: CCOC(=O)C1CSC(N1)CC2=CC=C(C=C2)OCC3=CC=C(C=C3)[N+](=O)[O-]