THZ-P1-2
Supplier | MedChemExpress |
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Product # | HY-136351-10 mg |
CAS # | 2058075-45-7 |
Pricing | 10 mg, USD $780.0 |
Biological Activity | THZ-P1-2 is a first-in-class and selective PI5P4K inhibitor, with an IC50 of 190 nM for PI5P4Kα. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4Kα/β/γ. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines[1]. |
Purity | 99.06% |
MWt | 531.61 |
Formula | C₃₁H₂₉N₇O₂ |