Dimethyl fumarate
Supplier | MedChemExpress |
---|---|
Product # | HY-17363-5 g |
CAS # | 624-49-7 |
Pricing | 5 g, USD $66.0 |
Synonyms | DMF |
MWt | 144.13 |
Formula | C₆H₈O₄ |
Biological Activity | Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research[1][2]. |
Purity | ≥98.0% |