PD 135158
PD 135158 is a Selective cholecystokinin type B (CCKB)/gastrin receptor agonist. In studies, PD- 135158 stimulates lipase release from isolated rat pancreatic acini dose dependently in a biphasic manner, with identical efficacy but lower potency compared to cholecystokinin octapeptide (CCK-8). PD 135158 is classified into Anti-Anxiety Agents, Central Nervous System Agents, Central Nervous System Depressants, Psychotropic Drugs, and Tranquilizing Agents.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD288 |
| CAS # | 130325-35-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | Cam 1028; Cam-1028; Cam1028; PD-135158; PD135158; PD 135158 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C42H61N5O11 |
| Exact Mass | 811.4368 |
| Molecular Weight | 811.9606 |
| Elemental Analysis | C, 62.13; H, 7.57; N, 8.63; O, 21.68 |
| IUPAC/Chemical Name | (2S,3R,4R,5R)-2,3,4,5,6-pentahydroxy-N-methylhexan-1-aminium 4-(((1S)-2-((2S)-3-(1H-indol-3-yl)-2-methyl-2-(((((2S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)oxy)carbonyl)amino)propanamido)-1-phenylethyl)amino)-4-oxobutanoate |
| InChi Key | CWJXTOIDFOBOKQ-YCSHSMMXSA-N |
| InChi Code | InChI=1S/C35H44N4O6.C7H17NO5/c1-33(2)24-16-17-34(33,3)28(18-24)45-32(44)39-35(4,19-23-20-36-26-13-9-8-12-25(23)26)31(43)37-21-27(22-10-6-5-7-11-22)38-29(40)14-15-30(41)42;1-8-2-4(10)6(12)7(13)5(11)3-9/h5-13,20,24,27-28,36H,14-19,21H2,1-4H3,(H,37,43)(H,38,40)(H,39,44)(H,41,42);4-13H,2-3H2,1H3/t24?,27-,28+,34?,35+;4-,5+,6+,7+/m10/s1 |
| SMILES Code | O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)C[NH2+]C.O=C([O-])CCC(N[C@@H](C1=CC=CC=C1)CNC([C@](NC(O[C@@H]2C(C3(C)C)(C)CCC3C2)=O)(C)CC4=CNC5=C4C=CC=C5)=O)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |