D-inositol-3-phosphate glycosyltransferase

The enzyme, which belongs to the GT-B fold superfamily, catalyses the first dedicated reaction in the biosynthesis of mycothiol. The substrate was initially believed to be inositol, but eventually shown to be D-myo-inositol 3-phosphate. A substantial conformational change occurs upon UDP binding, which generates the binding site for D-myo-inositol 3-phosphate.

• Supplier: Creative Enzymes
• Product #: EXWM-2480