Bavisant dihydrochloride
Bavisant dihydrochloride is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. Histamine H3 receptors reside on non-histamine neurons and regulate other neurotransmitters (e.g. acetylcholine, noradrenaline [norepinephrine]) suggesting that H3 antagonists have the potential to improve attention and impulsivity. Research indicates that H3 receptor antagonists due to their novel mechanism of action may have a unique treatment effect offering an important alternative for the treatment of ADHD.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD002 |
| CAS # | 1103522-80-0 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Bavisant dihydrochloride; JNJ-31001074-AAC; JNJ 31001074-AAC; JNJ31001074-AAC; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H31Cl2N3O3 |
| Exact Mass | 419.1742 |
| Molecular Weight | 420.37 |
| Elemental Analysis | C, 54.29; H, 7.43; Cl, 16.87; N, 10.00; O, 11.42 |
| IUPAC/Chemical Name | (4-cyclopropylpiperazin-1-yl)(4-(morpholinomethyl)phenyl)methanone dihydrochloride hydrate |
| InChi Key | BLFBQJUVAGIUBL-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H27N3O2.2ClH.H2O/c23-19(22-9-7-21(8-10-22)18-5-6-18)17-3-1-16(2-4-17)15-20-11-13-24-14-12-20;;;/h1-4,18H,5-15H2;2*1H;1H2 |
| SMILES Code | O=C(N1CCN(C2CC2)CC1)C3=CC=C(CN4CCOCC4)C=C3.[H]Cl.[H]Cl.[H]O[H] |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |