(R)-(-)-alpha-Methylhistamine dihydrobromide
(R)-(-)-alpha-Methylhistamine dihydrobromide is a potent and high affinity histamine H3 agonist (KD = 50.3 nM) displaying > 200-fold selectivity over H4 receptors. It inhibits H3-mediated histamine synthesis and release in the CNS at nanomolar concentrations, and induces H4-mediated eosinophil shape change (EC50 = 66 nM).
| Supplier | BOC Sciences |
|---|---|
| Product # | 868698-49-1 |
| Pricing | Inquire |
| Cas | 868698-49-1 |
| Molecular Weight | 287 |
| Molecular Formula | C6H11N3.2HBr |
| Canonical SMILES | CC(CC1=CN=CN1)N.Br.Br |