(R)-(-)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate, min. 98% [(R)-TiPSY]

• Supplier: Alfa Chemistry
• Product #: ACM791616552
• CAS #: 791616-55-2
• Synonyms: (S)-(+)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate; RD-0080; (11bR)-4-Hydroxy-2,6-bis(triphenylsilyl)dinaphtho-[2,1-d:1 inverted exclamation marka,2 inverted exclamation markaf]-1,3,2-dioxaphosphepin 4-oxide; Carreira SALDIPAC Ligand; (R)-(-)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate; (aS)-2,6-Bis(triphenylsilyl)-4-hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; (R)-(-)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (S)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthalene-2,2'-diyl hydrogen phosphate; SC-44139; 929097-92-7
• IUPAC Name: (13-hydroxy-13-oxo-16-triphenylsilyl-12,14-dioxa-13λ5-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-10-yl)-triphenylsilane
• MolecularFormula: C56H41O4PSi2
• MolecularWeight: 865.084g/mol
• Application:
  • A chiral phosphoric acid catalyst providing a convenient strategy for the enantioselective construction of protected primary amines and a highly stereoselective method for the reductive amination of heterocyclic amines.
  • Chiral phosphoric acid used for the enantioselective Biginelli and Biginelli-like reactions.
  • Chiral phosphoric acid organocatalyst used in the asymmetric, three-component Povarov reaction involving 2-hydroxystyrenes. An efficient method to access structurally diverse cis-disubstituted tetrahydroquinolines in high stereoselectivities of up to >99:1 dr and 97% ee.
  • A gold/chiral phosphoric acid catalyst used for the highly stereoselective, three-component reaction of salicylaldehydes, anilines, and alkynols to give aromatic spiroacetals in high yields and stereoselectivities.
  • The first highly enantioselective catalytic protocol for the reductive coupling of ketones and hydrozones.
  • Reagent-controlled regioselectivity enabled by dual activation.