| Supplier |
CD Formulation |
| Product # |
CDC10-0048 |
| CAS # |
222-468-7 |
| Pricing |
1, 5, 10, 25, 100 g in poly bottle, Inquire for price
|
| product1 |
Cosmetic Ingredients
|
| Molecular Formula |
C4H10O2S2
|
| Synonyms |
threo-1,4-Dimercapto-2,3-butanediol, Cleland’s reagent, DTT
|
| CAS Number |
3483-12-3
|
| Category |
Antioxidant Cosmetic Chemicals
|
| Purity |
≥98%
|
| Color |
White
|
| Physical State |
Powder
|
| Solubility |
H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow
|
| Quality Level |
200.0
|
| Storage |
2-8°C
|
| Boiling Point |
125 °C
|
| Melting Point |
41-44 °C (lit.)
|
| Density |
1.04 g/mL at 20 °C
|
| Product Description |
An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Typically, a seven fold lower concentration of DTT (100 mM) is needed than is used for 2-mercaptoethanol (5% v/v, 700 mM).
|
| Molecular Weight (g/mol) |
154.25
|
| Flash Point |
>230 °F
|
| MDL number |
MFCD00004877
|
| NACRES |
NA.21
|
| InChI Key |
VHJLVAABSRFDPM-UHFFFAOYSA-N
|
| SMILES |
O[C@H](CS)[C@H](O)CS
|
| InChI |
1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
|
| Hazard Codes |
Xn
|
| WGK Germany |
3.0
|
| RTECS |
EK1610000
|
| HS Code |
29309099.0
|
| Water Solubility |
Freely soluble
|
| Image |
3483-12-3
|