LSKL, Inhibitor of Thrombospondin TSP-1

Supplier Creative Peptides
Product # R1490
CAS # 283609-79-0
Pricing Inquire
MolecularFormula C21H42N6O5
MolecularWeight 458.6
Source Synthetic
Sequence
  • One Letter Code: LSKL   
  • Three Letter Code: Leu-Ser-Lys-Leu
Storage 4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingCondition Wet ice in continental US; may vary elsewhere
Explanation LSKL, Inhibitor of Thrombospondin (TSP-1) is a peptide derived from the latency-associated peptide, inhibits thrombospondin (TSP-1) activation of TGF-β and prevents the progression of hepatic damage and fibrosis.
ChemicalName (2S)-6-amino-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]hexanamide
InChI InChI=1S/C21H42N6O5/c1-12(2)9-14(23)19(30)27-17(11-28)21(32)25-15(7-5-6-8-22)20(31)26-16(18(24)29)10-13(3)4/h12-17,28H,5-11,22-23H2,1-4H3,(H2,24,29)(H,25,32)(H,26,31)(H,27,30)/t14-,15-,16-,17-/m0/s1
InChIKey YOKXDNNIFSAXBY-QAETUUGQSA-N
CanonicalSMILES CC(C)CC(C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)N)
Solubility DMSO : ≥ 100 mg/mL;H2O : 50 mg/mL (ultrasonic)
IsomericSMILES CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N)N
Purity ≥98%
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