Pomalidomide-PEG5-NH2 hydrochloride
Pomalidomide-PEG5-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.
Supplier | BOC Sciences |
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Product # | BP-100167 |
Pricing | Inquire |
Cas | 2357117-23-6 |
Molecular Weight | 573.04 |
Molecular Formula | C25H36N4O9.HCl |
Canonical SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCOCCN.Cl |