Alpha-Methylacyl-CoA Racemase (AMACR) Antibody
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) and (S) stereoisomers. The conversion to the (S) stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Supplier | Abbexa Ltd. |
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Product # | abx025595-400UL |
Pricing | 400 µl USD $601.75 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
UniProt Primary AC | Q9UHK6 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |