Sunitinib
Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1α. Sunitinib induces autophagy and apoptosis.
Supplier | Selleck Chemicals |
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Product # | S7781 |
Sku # | S7781-10mM/1mL |
Pricing | 10mM/1mL, $97.00 |
Citations for this product:
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bioRxiv - Cancer Biology 2020Quote: ... Sunitinib (Selleck Chemicals S7781) or a combination of etoposide (Selleck Chemicals S1225 ...
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bioRxiv - Cancer Biology 2023Quote: ... Sunitinib (Selleck Chemicals, S7781), recombinant human WIF1 (R&D systems ...