Cycloserine

Cycloserine is an analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. Cycloserine works as an antibiotic by inhibiting cell-wall biosynthesis in bacteria. As a cyclic analogue of D-alanine, cycloserine acts against two crucial enzymes important in the cytosolic stages of peptidoglycan synthesis: alanine racemase (Alr) and D-alanine:D-alanine ligase (Ddl). The first enzyme is a pyridoxal 5'-phosphate-dependent enzyme which converts the L-alanine to the D-alanine form. The second enzyme is involved in joining two of these D-alanine residues together by catalyzing the formation of the ATP-dependent D-alanine-D-alanine dipeptide bond between the resulting D-alanine molecules.

• Supplier: Ace Therapeutics
• Product #: SMD175
• CAS #: 68-41-7
• Synonym: D-cycloserine; Cycloserine; Seromycin; 68-41-7; Orientomycin; Oxamycin; Seromycin
• Product Category: Lab-use Small Molecule Drugs
• Chemical Formula: C3H6N2O2
• Exact Mass: 102.04293
• Molecular Weight: 102.09
• Elemental Analysis: C, 35.29; H, 5.92; N, 27.44; O, 31.34
• IUPAC/Chemical Name: (4R)-4-amino-1,2-oxazolidin-3-one
• InChi Key: DYDCUQKUCUHJBH-UWTATZPHSA-N
• InChi Code: InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
• SMILES Code: C1[C@H](C(=O)NO1)N
• Appearance: Solid powder
• Purity: >98% (or refer to the Certificate of Analysis)
• Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• Solubility: Soluble in DMSO, not in water
• Shelf Life: >2 years if stored properly
• Drug Formulation: This drug may be formulated in DMSO
• Stock Solution Storage: 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
• HS Tariff Code: 2934.99.9001
• Availability: 2 Weeks