Propargyl-PEG4-acid
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130481 |
| CAS # | 1415800-32-6 |
| Pricing | inquire |
| Biological Activity | Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib (HY-10997)-based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1]. |
| MWt | 260.28 |
| Formula | C₁₂H₂₀O₆ |