AEE 788-[d5]
Labelled AEE 788. AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis.
| Supplier | BOC Sciences |
|---|---|
| Product # | BLP-003228 |
| Pricing | Inquire |
| Cas | 1292840-54-0 |
| Molecular Weight | 445.61 |
| Molecular Formula | C27H27D5N6 |
| Canonical SMILES | CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5 |