Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide
Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide, a fluorescent (FRET) peptide substrate containing the wild-type amyloid precursor protein (APP) β-secretase cleavage site, is used to determine the β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). TOP is a potential β-secretase candidate and is involved in APP processing in vivo.
Supplier | BOC Sciences |
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Product # | BAT-014461 |
Pricing | Inquire |
Cas | 1802078-33-6 |
Molecular Weight | 2033.21 |
Molecular Formula | C87H129N27O28S |
Canonical SMILES | CC(C)C(C(=O)NC(CCCCN)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCNC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-])C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)CC3=CC(=O)OC4=C3C=CC(=C4)OC |