JIP-1 (153-163)
| Supplier | Creative Peptides |
|---|---|
| Product # | R0970 |
| CAS # | 438567-88-5 |
| Pricing | Inquire |
| LabelingTarget | c-Jun N-terminal kinase |
| Synonyms | TI-JIP |
| MolecularFormula | C61H104N20O14 |
| MolecularWeight | 1341.6 |
| Sequence | RPKRPTTLNLF(Disulfide bridge: Cys1 and Cys6,Cys9 and Cys14) |
| Storage | -20°C |
| Explanation | Selective peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). |
| Activity | Inhibitor |
| InChI | InChI=1S/C61H104N20O14/c1-32(2)28-41(51(87)74-40(49(65)85)30-36-16-8-7-9-17-36)75-53(89)43(31-46(64)84)76-52(88)42(29-33(3)4)77-56(92)47(34(5)82)79-57(93)48(35(6)83)78-55(91)45-22-15-27-81(45)59(95)39(20-13-25-71-61(68)69)73-50(86)38(19-10-11-23-62)72-54(90)44-21-14-26-80(44)58(94)37(63)18-12-24-70-60(66)67/h7-9,16-17,32-35,37-45,47-48,82-83H,10-15,18-31,62-63H2,1-6H3,(H2,64,84)(H2,65,85)(H,72,90)(H,73,86)(H,74,87)(H,75,89)(H,76,88)(H,77,92)(H,78,91)(H,79,93)(H4,66,67,70)(H4,68,69,71)/t34-,35-,37+,38+,39+,40+,41+,42+,43+,44+,45+,47+,48+/m1/s1 |
| InChIKey | BWQKOFMNXWAKES-QHYOMBHZSA-N |
| IsomericSMILES | C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)N)O |
| Appearance | White lyophilised solid |
| Purity | >98% |