Retrotransposon-Derived Protein PEG10 (PEG10) Antibody
PEG10 Antibody is a Rabbit Polyclonal antibody against PEG10. This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
Supplier | Abbexa Ltd. |
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Product # | abx002092-50UL |
Pricing | 50 µl USD $319.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | WB, IHC |
UniProt Primary AC | Q86TG7 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |