5'-O-DMT-2'-O-MOE-rG(iBu)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite

5'-O-DMT-2'-O-MOE-rG(iBu)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite, utilized in oligonucleotide synthesis, features a 5'-O-DMT protecting group and contains a diisopropylamino group for coupling with the next nucleotide. The nucleoside unit is guanosine (rG), modified with a 2'-O-methoxyethyl (MOE) group and isobutyryl (iBu) protection on the guanine amino group. It also contains a phosphoramidite group for solid-phase synthesis. It finds application in the construction of RNA sequences with enhanced stability and target specificity, suitable for various research applications including RNA-based therapeutics and gene editing.

• Supplier: BOC Sciences
• Product #: BRP-00604
• Molecular Weight: 1105.22
• Molecular Formula: C55H78N8O12P2