Niraparib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10619A-5 mg |
| CAS # | 1038915-64-8 |
| Pricing | 5 mg, USD $70.0 |
| Synonyms | MK-4827 hydrochloride |
| MWt | 356.85 |
| Formula | C₁₉H₂₁ClN₄O |
| Biological Activity | Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3]. |
| Purity | 99.80% |