PHA 543613 dihydrochloride
PHA-543613 dihydrochloride acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1637 |
| CAS # | 478148-58-2 (2HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | PHA 543613 dihydrochloride; PHA-543613 dihydrochloride; PHA543613 dihydrochloride; PHA 543613. 2HCl; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C15H19Cl2N3O2 |
| Molecular Weight | 344.24 |
| Elemental Analysis | C, 52.34; H, 5.56; Cl, 20.60; N, 12.21; O, 9.30 |
| IUPAC/Chemical Name | (R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide dihydrochloride |
| InChi Key | USJDQOUQSDDWPO-GXKRWWSZSA-N |
| InChi Code | InChI=1S/C15H17N3O2.2ClH/c19-15(12-7-11-3-6-20-14(11)8-16-12)17-13-9-18-4-1-10(13)2-5-18;;/h3,6-8,10,13H,1-2,4-5,9H2,(H,17,19);2*1H/t13-;;/m0../s1 |
| SMILES Code | O=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4.[H]Cl.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |