N6-Chloroacetyl-5'-O-DMT-N1-methyl-2'-O-TBDMS-adenosine 3'-CED phosphoramidite

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N6-Chloroacetyl-5'-O-DMT-N1-methyl-2'-O-TBDMS-adenosine 3'-CED phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It comprises several modifications, including a chloroacetyl group at the N6 position, a dimethoxytrityl (DMT) protecting group at the 5'-end, a methyl group at the N1 position, a 2'-O-tert-butyldimethylsilyl (TBDMS) modification at the ribose sugar, and a controlled-efficiency (CED) phosphoramidite backbone at the 3'-end. This complex modification pattern enhances stability and functionality, making it suitable for various molecular biology applications, including gene expression studies and therapeutic RNA-based treatments.

Supplier	BOC Sciences
Product #	BRP-00530
Pricing	Inquire
Cas	434329-10-9
Molecular Weight	944.57
Molecular Formula	C48H63ClN7O7PSi
Canonical SMILES	N#CCCOP(OC1C(OC(N2C=NC3=C2N=CN(C3=NC(=O)CCl)C)C1O[Si](C)(C)C(C)(C)C)COC(C=4C=CC=CC4)(C=5C=CC=CC5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

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