| Application |
Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research s. These materials have been used in many s such as signal amplification in bioassays and in drug delivery s. These alkyne-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC), strain-promoted alkyne-azide cycloaddition (SPAAC), or thiol-yne click reactions. Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical s.
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