(S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine

• Supplier: Alfa Chemistry
• Product #: ACM112022818
• CAS #: 112022-81-8
• Synonyms: AKOS015840981; (S)-1-methyl-3,3-diphenyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; MFCD00078439; (S)- Methyl-CBS-oxazaborolidine; ZINC169743318; (S)-tetrahydro-1-methyl-3,3-diphenyl-1 H,3 H-pyrrolo[1,2-c][1,3,2] oxazaborole; (S)-1-methyl-3,3-diphenylhexahydropyrrolo-[1,2-c][1,3,2]oxazaborole; (S)-tetrahydro-1-methyl-3,3-diphenyl-1 H,3H-pyrrolo[1,2-c]-[1,3,2]oxazaborole; (S)-Me-CBS; Corey catalyst
• IUPAC Name: (3aS)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole
• MolecularFormula: C18H20BNO
• MolecularWeight: 277.174g/mol
• Application:
  • Convenient catalyst for the enantioselective borane reduction of ketones at ambient temperatures.
  • Asymmetric synthesis of α-chiral hydroxyalkylphosphines via a catalytic, enantioselective reduction of acylphosphines.
  • Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: Stereospecific formation of diarylalkanes and triarylmethanes.
  • Enantioselective reduction of prochiral ketones with NaBH4/Me2SO4/(S)-Me-CBS.