CX-5461 dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13323A-10 mg |
| Pricing | 10 mg, USD $192.0 |
| Biological Activity | CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM). |
| Purity | 98.24% |
| MWt | 586.54 |
| Formula | C₂₇H₂₉Cl₂N₇O₂S |