Androgen receptor antagonist 1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130992-10 mM * 1 mL |
| CAS # | 1338812-36-4 |
| Pricing | 10 mM * 1 mL, USD $495.0 |
| Biological Activity | Androgen receptor antagonist 1 is an orally available full androgen receptor (AR) antagonist with an IC50 of 59 nM[1]. Androgen receptor antagonist 1 (Compound 6) can be used in the synthesis of PROTAC AR degraders, which results 24% and 47 % AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively[2]. |
| Purity | 99.39% |
| MWt | 416.9 |
| Formula | C₂₁H₂₅ClN₄O₃ |