SPR inhibitor 3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-115510-10 mM * 1 mL |
| CAS # | 1292285-54-1 |
| Pricing | 10 mM * 1 mL, USD $143.0 |
| Synonyms | SPRi3 |
| MWt | 262.3 |
| Formula | C₁₄H₁₈N₂O₃ |
| Biological Activity | SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels[1][2][3]. |
| Purity | 99.91% |