(Z)-Ethyl 3-(4-Benzylphenyl)-2-cyanobut-2-enoate

(Z)-Ethyl 3-(4-Benzylphenyl)-2-cyanobut-2-enoate is an intermediate in synthesizing Barbadin (B118250), a selective β-arrestin/β2-adaptin inhibitor. It selectively inhibits the interaction between b-arrestin and the b2-adaptin subunit of the clathrin adaptor protein AP2 without affecting the formation of receptor/b-arrestin complexes.

• Supplier: BOC Sciences
• Product #: BB065586
• Molecular Weight: 305.37
• Molecular Formula: C20H19NO2