ob/ob Mouse
Sequencing of RT-PCR products revealed a nonsense mutation in arginine codon 105 resulting from a C-to-T point mutation. The 16 kDa leptin protein, expressed predominantly in adipose tissue of normal mice, is missing from homozygous mutant mice
| Supplier | Ace Therapeutics |
|---|---|
| Product # | DMM-001006 |
| Pricing | Inquiry |
| Synonyms | Leptin |
| Category | Mouse Models |
| disease type | T2DM |
| Strain Name | B6.Cg-Lepob/J |
| Background Strain | B6.Cg |
| SPF | Yes |
| Research Application | Diabetes |
| Target Name | Lep |
| Gene ID | 16846 |