eIF4A3-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-101513-10 mM * 1 mL |
| CAS # | 2095486-67-0 |
| Pricing | 10 mM * 1 mL, USD $622.0 |
| Biological Activity | eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD[1]. |
| Purity | 99.70% |
| MWt | 588.88 |
| Formula | C₂₉H₂₃BrClN₅O₂ |